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Interpretation of the scores


Profile-derived Scores for the Alignment (negative scores are irrelevant and not shown)




Almost all the aligned positions score positively and there are two largish reliable regions (see below). This is a good indication that this is a good alignment.


Reliability Scores (those residues that are reliably aligned are marked with an '@')
     Target   EAETIVVKSGDSLWTLANEYEVEWTALYEANSDAAVIYVGQELVL-PQ
              -----@@@@@@@@@@@@@@@----------------@@@@@@@-----  
     Template DSITYRVRKGDSLSSIAKRHGVNIKDVMRWNSDTANLQPGDKLTLFVK

Template secondary structure (DSSP)
     Target   EAETIVVKSGDSLWTLANEYEVEWTALYEANSDAAVIYVGQELVL-PQ
              --EEEEE-TT--HHHHHHHHT--HHHHHHH-SS----STTEEEEE---  
     Template DSITYRVRKGDSLSSIAKRHGVNIKDVMRWNSDTANLQPGDKLTLFVK

Template residue conservation (HSSP, the higher the score the greater the conservation)
     Target   EAETIVVKSGDSLWTLANEYEVEWTALYEANSDAAVIYVGQELVL-PQ
              512270941895811982324512236111910211602931825344  
     Template DSITYRVRKGDSLSSIAKRHGVNIKDVMRWNSDTANLQPGDKLTLFVK

Note that the residues conserved in the HSSP alignment are conserved here too and that they co-incide for the most part with the high-scoring regions of the alignment. The correspondence with the HSSP conservation scores confirms that this is a good match.


Tree-determinant residues
     Target   EAETIVVKSGDSLWTLANEYEVEWTALYEANSDAAVIYVGQELVL-PQ
              ----45C54432233046252688140456C32344655505278---  
     Template DSITYRVRKGDSLSSIAKRHGVNIKDVMRWNSDTANLQPGDKLTLFVK

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